The relationship of chronic alcohol use to the
structure and function of the body is reasonably well understood. Heavy alcohol use causes a variety of changes
to the body that lead to an increase in morbidity and mortality.
Research shows that chronic alcohol use also damages
the immune system and the nervous system.
Thus chronic users are at high risk for a variety of infections and
neurological complications.
Additionally, many alcoholics suffer from malnutrition, in part because
they do not consume a variety of foods.
With the deterioration of the liver, stomach, and pancreas, chronic
heavy drinkers also have poor absorption and metabolism of many nutrients.
Fetal Alcohol
Syndrome and Fetal Alcohol Effects
A growing body scientific evidence indicates that
alcohol use by pregnant women can result in birth defects in unborn
children. When alcohol crosses the placenta,
it enters the fetal bloodstream in a concentration equal to that in the
mother’s bloodstream. Because of the
underdeveloped nature of the fetal liver, this alcohol is oxidized much more
slowly than the alcohol in the mother.
During this time of slow detoxification, the developing fetus is certain
to be overexposed to the toxic effects of alcohol. Mental retardation frequently develops.
This exposure has additional disastrous consequences
for the developing fetus. Low birth
weight, facial abnormalities (e.g., small head, widely spread eyes), and heart
problems are often seen in such infants.
This combination of effects is called fetal alcohol syndrome. Recent estimates indicate that the full
expression of this syndrome occurs at a rate of between 1 and 3 per 1000
births. Partial expression (fetal
alcohol effects [FAE]) can be seen in 3 to 9 per 1000 live births. In addition, it is likely that many cases of
FAE go undetected.
Is there a safe limit to the number of drinks a
woman can consume during pregnancy? Since no one can accurately predict the
effect of drinking even small amounts of alcohol during pregnancy, the wisest
plan is to avoid alcohol altogether.
Because
of the critical growth and development that occur during the first months of fetal
life, women who have any reason to suspect they are pregnant should stop all
alcohol consumption. Furthermore, women
who are planning to become pregnant and women who are not practicing effective
contraception must also consider keeping their alcohol use to a minimum.
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